Re: Personalized Medicine and Cancer Supportive Care: Appropriate Use of Colony-Stimulating Factor Support of Chemotherapy
نویسندگان
چکیده
منابع مشابه
Personalized medicine and cancer supportive care: appropriate use of colony-stimulating factor support of chemotherapy.
Myelosuppression and neutropenic complications remain major dose-limiting toxicities of cancer chemotherapy resulting in increased morbidity, mortality, and costs ( 1 , 2 ). The major factors that are associated with the risk of mortality from febrile neutropenia (FN) include older age, cancer type and stage, documented infection, bacteremia, sepsis, venous thromboembolism, and the number of se...
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15 صفحه اولMaximizing the outcomes in cancer patients receiving chemotherapy through optimal use of colony-stimulating factor.
OBJECTIVE To discuss clinical data on the utility of 2 colony-stimulating factors (CSFs), filgrastim and pegfilgrastim, in reducing the risk and incidence of neutropenic complications with chemotherapy. DATA SOURCES This article reviews the data from the clinical studies for both pegfilgrastim and filgrastim. Additionally, data from large, population-based retrospective analyses on the clinic...
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In this study granulocyte-macrophage colony stimulating factor (CSF) was prepared from rabbit and guinea pig lung tissues. The biological activity of these CSFs was measured on semisolid agar culture and compared with those of mouse and rat. Weight of animals, incubation time and cross-reactivity of CSFs with different bone marrow sources were also investigated. The results showed that both...
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background: recently, the use of granulocyte colony-stimulating factor (g-csf) has been proposed to improve pregnancy outcomes in reproductive medicine. objective: a systematic review of the current use of g-csf in patients who have difficulty conceiving and maintaining pregnancy was performed. materials and methods: two electronic databases (pubmed/ medline and scopus) were searched. study sel...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 2011
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djr439